Laboratory Specialty Services
Medchemexpress LLC TAK-285 | 871026-44-7 | C26H25ClF3N5O3 | 50 MG
TAK-285 is a potent, selective, ATP-competitive, and orally active inhibitor of HER2 and EGFR (HER1), with IC50 values of 17 nM and 23 nM, respectively. It demonstrates greater than 10-fold selectivity for HER1/2 compared to HER4, and exhibits less potency against MEK1/5, c-Met, Aurora B, Lck, and CSK, among others. This compound has shown effective antitumor activity and can cross the blood-brain barrier (BBB).
- Potent and selective inhibition
- ATP-competitive
- Orally active
- Antitumor activity
- Blood-brain barrier penetration
- Inhibitory activity against BT-474 cells
- Preclinical efficacy in xenograft models
Hampton Research HR2-944-83/Index #83 (G11), 185 ml - 0.2 M Magnesium chloride hexahydrate, 0.1 M BIS-TRIS pH 6.5, 25% w/v Polyethylene glycol 3,350
HR2-944-83/Index #83 (G11), 185 ml - 0.2 M Magnesium chloride hexahydrate, 0.1 M BIS-TRIS pH 6.5, 25% w/v Polyethylene glycol 3,350. Please note items from this supplier are non-returnable.
Hampton Research HR2-944-37/Index #37 (D1), 185 ml - 25% w/v Polyethylene glycol 1,500
HR2-944-37/Index #37 (D1), 185 ml - 25% w/v Polyethylene glycol 1,500. Please note items from this supplier are non-returnable.
Hampton Research HR2-926-C6/Grid Screen PEG 6000 #C6, 185 ml - 0.1 M BICINE pH 9.0, 20% w/v Polyethylene glycol 6,000
HR2-926-C6/Grid Screen PEG 6000 #C6, 185 ml - 0.1 M BICINE pH 9.0, 20% w/v Polyethylene glycol 6,000. Please note items from this supplier are non-returnable.
Hampton Research HR2-939-20/StockOptions Sodium Cacodylate #20 pH 7.0, 185 ml
HR2-939-20/StockOptions Sodium Cacodylate #20 pH 7.0, 185 ml. Please note items from this supplier are non-returnable.
Crescent Chemical Co Inc EPA600 BASE/NEU MIX1 14COMP1ML
CLP Semivolatile Priority Pollutant Standards, BaseNeutrals Mix 1, 14 Components Bis(2-chloroethoxy)methane, Bis(2-chloroethyl)ether, Bis(2-chloroisopropyl)ether, Bis(2-ethylhexyl)phthalate, 4-Bromophenylphenyl ether, Butyl benzyl phthalate, 4-Chlor
Crescent Chemical Co Inc SERVALYT™ 3-10 ISO-DALT
SERVALYT™ 3-10 Iso-Dalt 40 % (w/v) solution in water Iso-Dalt quality; special 2D grade to be used in 2D electrophoresis. Size - 2ML Storage Conditions - +2 °C TO +8 °C Catalog Number - 42951.04
Hampton Research HR2-944-75/Index #75 (G03), 185 ml - 0.2 M Lithium sulfate monohydrate, 0.1 M BIS-TRIS pH 6.5, 25% w/v Polyethylene glycol 3,350
HR2-944-75/Index #75 (G03), 185 ml - 0.2 M Lithium sulfate monohydrate, 0.1 M BIS-TRIS pH 6.5, 25% w/v Polyethylene glycol 3,350. Please note items from this supplier are non-returnable.
Hampton Research MEMBFAC NO23 185ML
HR2-920-23/MembFac #23 (B11), 185 ml - 0.1 M Lithium sulfate monohydrate, 0.1 M ADA pH 6.5, 12% w/v Polyethylene glycol 4,000, 2% v/v 2-Propanol. Please note items from this supplier are non-returnable.
Medchemexpress LLC 2-chloro-4-((1R)-1-(4-(4-fluoro-2-oxopyridin-1(2H)-yl)phenyl)ethylamino)-N-(5-(trifluoromethyl)pyridin-2-yl)... | 871026-44-7 | MFCD22124520 | 99.0% | 547.96 | C26H25ClF3N5O3 | 10 MG
TAK-285 is a potent, selective, ATP-competitive, orally active inhibitor of HER2 and EGFR (HER1) used in oncology and kinase research. It exhibits low-nanomolar potency against HER2 and EGFR, shows selectivity over related kinases, and has demonstrated antitumor activity with the ability to cross the blood-brain barrier.
- Potent ATP-competitive inhibitor of HER2 and EGFR with low-nanomolar IC50 values.
- Greater than 10-fold selectivity for HER1/2 compared with HER4.
- Demonstrated antitumor activity and ability to penetrate the blood-brain barrier.
- High purity suitable for biochemical and cellular assays.
- Available as solid packs and as a 10 mM solution in DMSO for stock preparation.
- Well characterized by molecular formula and molecular weight for compound verification.
TARGETMOL CHEMICALS INC COMPOUND CDY9 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 uM for hCA II. purity: 99%
Biocare Medical, LLC Fluoro Care Anti-Fade Mountant - 5.0 ml
Fluoro Care Anti-Fade Mountant is an innovative, liquid-based, anti-fade mounting medium designed especially for the permanent preservation of fluorescent specimens. Fluoro Care is to be used with tissue sections stained with a multitude of fluorescent dyes. Fluoro Care is compatible with DyLightTM Fluors, Alexa Fluors®, fluorescein, rhodamine, Texas Red and stained specimens.
![Medchemexpress LLC N-[5-(3,5-dicyano-1,4-dihydro-1,2,6-trimethyl-4-pyridinyl)-6-fluoro-7-methyl-1H-indazol-3-yl] | 2377576-35-5 | 99.7% | 468.53 | C27H25FN6O | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000264722.png-250.jpg)
Medchemexpress LLC N-[5-(3,5-dicyano-1,4-dihydro-1,2,6-trimethyl-4-pyridinyl)-6-fluoro-7-methyl-1H-indazol-3-yl] | 2377576-35-5 | 99.7% | 468.53 | C27H25FN6O | 5 MG
BAY-3827 is a potent, selective small-molecule inhibitor of AMP-activated protein kinase (AMPK) used as a chemical probe in preclinical research. It demonstrates antiproliferative activity in androgen-dependent prostate cancer cell models and is supplied as a solid with reported high purity for biochemical and cellular studies.
- Potent and selective AMPK inhibitor.
- Demonstrated antiproliferative activity in androgen-dependent prostate cancer cell lines.
- Suitable for biochemical and cellular assays as a research chemical.
- Provided as a solid in small-milligram quantities for early-stage experiments.
- Reported high purity suitable for analytical and biological studies.